Target：RhoBTB1/2

Fields：Ubiquitin mediated proteolysis

Gene Name：RHOBTB1/RHOBTB2

Protein Name：Rho-related BTB domain-containing protein 1/2

Human Gene Id：23221/9886

Human Swiss Prot No：O94844/Q9BYZ6

Mouse Gene Id：69288/246710

Immunogen：The antiserum was produced against synthesized peptide derived from human RHBT2. AA range:61-110

Specificity：RhoBTB1/2 Polyclonal Antibody detects endogenous levels of RhoBTB1/2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：RHOBTB1;KIAA0740;Rho-related BTB domain-containing protein 1;RHOBTB2;DBC2;KIAA0717;Rho-related BTB domain-containing protein 2;Deleted in breast cancer 2 gene protein;p83

Observed Band(KD)：83kD

Background： The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008],

Function：similarity:Belongs to the small GTPase superfamily. Rho family.,similarity:Contains 2 BTB (POZ) domains.,tissue specificity:Ubiquitous, with highest levels in skeletal muscle, placenta, testis, stomach, and kidney, followed by uterus and adrenal gland. Expressed in a variety of fetal tissues.,

Subcellular Location：intracellular,cytosol,plasma membrane,

Expression：Ubiquitous, with highest levels in skeletal muscle, placenta, testis, stomach, and kidney, followed by uterus and adrenal gland. Expressed in a variety of fetal tissues.