Target：P2RY1
Fields：Rap1 signaling pathway;Neuroactive ligand-receptor interaction;Platelet activation;Taste transduction
Gene Name：P2RY1
Protein Name：P2Y purinoceptor 1 (P2Y1) (ATP receptor) (Purinergic receptor)
Human Gene Id：5028
Human Swiss Prot No：P47900
Mouse Swiss Prot No：P49650
Rat Swiss Prot No：P49651
Immunogen：Synthesized peptide derived from human protein . at AA range: 130-210
Specificity：P2RY1 Polyclonal Antibody detects endogenous levels of protein.
Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500-2000 ELISA 1:5000-20000
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD)：41kD
Background：purinergic receptor P2Y1(P2RY1) Homo sapiens The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008],
Function：function:Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.,induction:Repressed by the P2Y1 receptor-specific antagonists A3P5PS, A3P5P and A2P5P. These inhibit calcium ion mobilization and shape change in platelets.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Subcellular Location：Cell membrane ; Multi-pass membrane protein .
Expression： Blood,Brain,Lung,Placenta,Platelet,
