Target:PABP3
Fields:mRNA surveillance pathway;RNA degradation
Gene Name:PABPC3
Protein Name:Polyadenylate-binding protein 3
Human Gene Id:5042
Human Swiss Prot No:Q9H361
Immunogen:The antiserum was produced against synthesized peptide derived from human PABPC3. AA range:352-401
Specificity:PABP3 Polyclonal Antibody detects endogenous levels of PABP3 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000.IHC:1:50-300 ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:PABPC3;PABP3;PABPL3;Polyadenylate-binding protein 3;PABP-3;Poly(A)-binding protein 3;Testis-specific poly(A)-binding protein
Observed Band(KD):70kD
Background: Messenger RNA stability and translation initiation are extensively under the control of poly(A)-binding proteins (PABP). See PABPC1 (MIM 604679) for background information.[supplied by OMIM, Jul 2002],
Function:function:Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Binds poly(A) with a slightly lower affinity as compared to PABPC1.,similarity:Belongs to the polyadenylate-binding protein type-1 family.,similarity:Contains 1 PABC domain.,similarity:Contains 4 RRM (RNA recognition motif) domains.,tissue specificity:Testis specific.,
Subcellular Location:Cytoplasm .
Expression:Testis specific.