Target：Pax-1

Gene Name：PAX1

Protein Name：Paired box protein Pax-1

Human Gene Id：5075

Human Swiss Prot No：P15863

Mouse Swiss Prot No：P09084

Immunogen：The antiserum was produced against synthesized peptide derived from human Pax-1. AA range:318-367

Specificity：Pax-1 Polyclonal Antibody detects endogenous levels of Pax-1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：PAX1;HUP48;Paired box protein Pax-1;HuP48

Observed Band(KD)：36kD

Background： This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. This gene plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. This gene is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene. Mutations in this gene are also associated with vertebral malformations. [provided by RefSeq, Mar 2012],

Function：function:This protein is a transcriptional activator. It may play a role in the formation of segmented structures of the embryo. May play an important role in the normal development of the vertebral column.,similarity:Contains 1 paired domain.,

Subcellular Location：Nucleus.