Target：Rho GDIγ

Fields：Neurotrophin signaling pathway;Vasopressin-regulated water reabsorption

Gene Name：ARHGDIG

Protein Name：Rho GDP-dissociation inhibitor 3

Human Gene Id：398

Human Swiss Prot No：Q99819

Mouse Swiss Prot No：Q62160

Immunogen：Synthesized peptide derived from Rho GDIγ . at AA range: 110-190

Specificity：Rho GDIγ Polyclonal Antibody detects endogenous levels of Rho GDIγ protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ARHGDIG;Rho GDP-dissociation inhibitor 3;Rho GDI 3;Rho-GDI gamma

Observed Band(KD)：25kD

Background： The GDP-dissociation inhibitors (GDIs) play a primary role in modulating the activation of GTPases by inhibiting the exchange of GDP for GTP. See ARHGDIB (MIM 602843).[supplied by OMIM, Nov 2010],

Function：function:Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.,similarity:Belongs to the Rho GDI family.,tissue specificity:Primarily expressed in pancreas and brain.,

Subcellular Location：Cytoplasm.

Expression：Primarily expressed in pancreas and brain.