Target：PGRC1

Gene Name：PGRMC1 HPR6.6 PGRMC

Protein Name：Membrane-associated progesterone receptor component 1 (mPR)

Human Gene Id：10857

Human Swiss Prot No：O00264

Mouse Swiss Prot No：O55022

Rat Swiss Prot No：P70580

Immunogen：Synthesized peptide derived from human protein . at AA range: 20-100

Specificity：PGRC1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：21kD

Background： This gene encodes a putative membrane-associated progesterone steroid receptor. The protein is expressed predominantly in the liver and kidney. [provided by RefSeq, Mar 2010],

Function：domain:The cytochrome b5 heme-binding domain lacks the conserved iron-binding His residues at positions 107 and 131.,function:Receptor for progesterone.,similarity:Belongs to the cytochrome b5 family. MAPR subfamily.,similarity:Contains 1 cytochrome b5 heme-binding domain.,tissue specificity:Widely expressed, with highest expression in liver and kidney.,

Subcellular Location：Microsome membrane ; Single-pass membrane protein . Smooth endoplasmic reticulum membrane ; Single-pass membrane protein . Mitochondrion outer membrane ; Single-pass membrane protein ; Extracellular side .

Expression：Widely expressed, with highest expression in liver and kidney. Expressed by endometrial glands and stroma (at protein level) (PubMed:23793472).