Target：PGLS

Fields：Pentose phosphate pathway;Metabolic pathways;Carbon metabolism

Gene Name：PGLS

Protein Name：6-phosphogluconolactonase

Human Gene Id：25796

Human Swiss Prot No：O95336

Mouse Swiss Prot No：Q9CQ60

Immunogen：The antiserum was produced against synthesized peptide derived from human PGLS. AA range:191-240

Specificity：PGLS Polyclonal Antibody detects endogenous levels of PGLS protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：PGLS;6-phosphogluconolactonase;6PGL

Observed Band(KD)：30kD

Background：catalytic activity:6-phospho-D-glucono-1,5-lactone + H(2)O = 6-phospho-D-gluconate.,function:Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.,pathway:Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.,similarity:Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.,

Function：catalytic activity:6-phospho-D-glucono-1,5-lactone + H(2)O = 6-phospho-D-gluconate.,function:Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.,pathway:Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.,similarity:Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.,

Subcellular Location：Cytoplasm .

Expression： Brain,Cajal-Retzius cell,Fetal brain cortex,Uterus,