Target：PDP2

Gene Name：PDP2

Protein Name：[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2 mitochondrial

Human Gene Id：57546

Human Swiss Prot No：Q9P2J9

Immunogen：Synthesized peptide derived from PDP2 . at AA range: 70-150

Specificity：PDP2 Polyclonal Antibody detects endogenous levels of PDP2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：PDP2;KIAA1348;[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial;PDP 2;Pyruvate dehydrogenase phosphatase catalytic subunit 2;PDPC 2

Observed Band(KD)：59kD

Background： This gene is a mitochondrial protein that functions as a phosphatase and is involved in the enzymatic resetting of the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2016],

Function：catalytic activity:[Pyruvate dehydrogenase (acetyl-transferring)] phosphate + H(2)O = [pyruvate dehydrogenase (acetyl-transferring)] + phosphate.,cofactor:Binds 2 magnesium ions per subunit.,function:Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.,similarity:Belongs to the PP2C family.,subunit:Heterodimer of a catalytic subunit and a FAD protein of unknown function.,

Subcellular Location：Mitochondrion matrix .

Expression： Brain,