Target:PITSLRE
Gene Name:CDK11B
Protein Name:Cyclin-dependent kinase 11B
Human Gene Id:984
Human Swiss Prot No:P21127
Mouse Gene Id:12537
Mouse Swiss Prot No:P24788
Immunogen:The antiserum was produced against synthesized peptide derived from human CDC2L1. AA range:10-59
Specificity:PITSLRE Polyclonal Antibody detects endogenous levels of PITSLRE protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:CDK11B;CDC2L1;CDK11;PITSLREA;PK58;Cyclin-dependent kinase 11B;Cell division cycle 2-like protein kinase 1;CLK-1;Cell division protein kinase 11B;Galactosyltransferase-associated protein kinase p58/GTA;PITSLRE serine/threonine-prot
Observed Band(KD):92kD
Background: This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014],
Function:caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,
Subcellular Location:Cytoplasm. Nucleus.
Expression:Expressed ubiquitously. Some evidence of isoform-specific tissue distribution.