Target：FTβ

Fields：Terpenoid backbone biosynthesis

Gene Name：FNTB

Protein Name：Protein farnesyltransferase subunit beta

Human Gene Id：2342

Human Swiss Prot No：P49356

Mouse Gene Id：110606

Mouse Swiss Prot No：Q8K2I1

Rat Gene Id：64511

Rat Swiss Prot No：Q02293

Immunogen：The antiserum was produced against synthesized peptide derived from human FNTB. AA range:255-304

Specificity：FTβ Polyclonal Antibody detects endogenous levels of FTβ protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：FNTB;Protein farnesyltransferase subunit beta;FTase-beta;CAAX farnesyltransferase subunit beta;Ras proteins prenyltransferase subunit beta

Observed Band(KD)：49kD

Background：catalytic activity:Farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.,cofactor:Binds 1 zinc ion per subunit.,function:Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.,similarity:Belongs to the protein prenyltransferase subunit beta family.,similarity:Contains 5 PFTB repeats.,subunit:Heterodimer of an alpha and a beta subunit.,

Function：catalytic activity:Farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.,cofactor:Binds 1 zinc ion per subunit.,function:Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.,similarity:Belongs to the protein prenyltransferase subunit beta family.,similarity:Contains 5 PFTB repeats.,subunit:Heterodimer of an alpha and a beta subunit.,

Subcellular Location：cytosol,microtubule associated complex,protein farnesyltransferase complex,

Expression： Neuroblastoma,Placenta,Retina,