Target：PIGW

Fields：Glycosylphosphatidylinositol (GPI)-anchor biosynthesis;Metabolic pathways

Gene Name：PIGW

Protein Name：Phosphatidylinositol-glycan biosynthesis class W protein (PIG-W) (EC 2.3.-.-)

Human Gene Id：284098

Human Swiss Prot No：Q7Z7B1

Mouse Swiss Prot No：Q8C398

Rat Swiss Prot No：Q7TSN4

Immunogen：Synthesized peptide derived from human protein . at AA range: 370-450

Specificity：PIGW Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：55kD

Background： Glycosylphosphatidylinositol (GPI) is a complex glycolipid that anchors many proteins to the cell surface. PIGW acts in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol (Murakami et al., 2003 [PubMed 14517336]).[supplied by OMIM, Mar 2008],

Function：function:Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins.,pathway:Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.,similarity:Belongs to the PIGW family.,

Subcellular Location：Endoplasmic reticulum membrane ; Multi-pass membrane protein .

Expression： Brain,Epithelium,