Target:PI-9
Fields:Amoebiasis
Gene Name:SERPINB9
Protein Name:Serpin B9
Human Gene Id:5272
Human Swiss Prot No:P50453
Immunogen:The antiserum was produced against synthesized peptide derived from human SERPINB9. AA range:241-290
Specificity:PI-9 Polyclonal Antibody detects endogenous levels of PI-9 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:SERPINB9;PI9;Serpin B9;Cytoplasmic antiproteinase 3;CAP-3;CAP3;Peptidase inhibitor 9;PI-9
Observed Band(KD):40kD
Background: This gene encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Mar 2012],
Function:function:Granzyme B inhibitor.,similarity:Belongs to the serpin family.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,
Subcellular Location:Cytoplasm.
Expression: Bone marrow,Human esophagus tumor,Placenta,Testis,