Target：PHAPI2

Gene Name：ANP32B

Protein Name：Acidic leucine-rich nuclear phosphoprotein 32 family member B

Human Gene Id：10541

Human Swiss Prot No：Q92688

Mouse Gene Id：67628

Mouse Swiss Prot No：Q9EST5

Rat Gene Id：170724

Rat Swiss Prot No：Q9EST6

Immunogen：The antiserum was produced against synthesized peptide derived from human ANP32B. AA range:1-50

Specificity：PHAPI2 Polyclonal Antibody detects endogenous levels of PHAPI2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ANP32B;APRIL;PHAPI2;Acidic leucine-rich nuclear phosphoprotein 32 family member B;Acidic protein rich in leucines;Putative HLA-DR-associated protein I-2;PHAPI2;Silver-stainable protein SSP29

Observed Band(KD)：29kD

Background：function:Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity.,similarity:Belongs to the ANP32 family.,similarity:Contains 4 LRR (leucine-rich) repeats.,subcellular location:Accumulates in the nuclei at the S phase.,tissue specificity:Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.,

Function：function:Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity.,similarity:Belongs to the ANP32 family.,similarity:Contains 4 LRR (leucine-rich) repeats.,subcellular location:Accumulates in the nuclei at the S phase.,tissue specificity:Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.,

Subcellular Location：[Isoform 1]: Nucleus . Cytoplasm . Accumulates in the nuclei at the S phase. .; [Isoform 2]: Cytoplasm. Lacks a nuclear localization signal.

Expression：Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.