Target：PSP

Gene Name：PSPN

Protein Name：Persephin

Human Gene Id：5623

Human Swiss Prot No：O60542

Mouse Swiss Prot No：O70300

Rat Gene Id：25525

Rat Swiss Prot No：O70301

Immunogen：The antiserum was produced against synthesized peptide derived from the C-terminal region of human PSPN. AA range:101-150

Specificity：PSP Polyclonal Antibody detects endogenous levels of PSP protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：PSPN;Persephin;PSP

Observed Band(KD)：16kD

Background：persephin(PSPN) Homo sapiens This gene encodes a secreted ligand of the GDNF (glial cell line-derived neurotrophic factor) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. This protein may play a role in cell death, and nervous system development and function. Elevated expression of this gene has been observed in oral squamous cell carcinoma. [provided by RefSeq, Aug 2016],

Function：function:Exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons.,similarity:Belongs to the TGF-beta family. GDNF subfamily.,subunit:Homodimer; disulfide-linked.,

Subcellular Location：Secreted.