Target：PSG3
Gene Name：PSG3
Protein Name：Pregnancy-specific beta-1-glycoprotein 3
Human Gene Id：5671
Human Swiss Prot No：Q16557
Immunogen：Synthesized peptide derived from the Internal region of human PSG3.
Specificity：PSG3 Polyclonal Antibody detects endogenous levels of PSG3 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：PSG3;Pregnancy-specific beta-1-glycoprotein 3;PS-beta-G-3;PSBG-3;Pregnancy-specific glycoprotein 3;Carcinoembryonic antigen SG5
Molecular Weight(Da)：48kD
Background： The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM
Function：developmental stage:PSBG are produced in high quantity during pregnancy.,similarity:Belongs to the immunoglobulin superfamily. CEA family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,
Subcellular Location：Secreted .
Expression： Colon,Placenta,Testis,
