Target：PPP1R14D

Gene Name：PPP1R14D

Protein Name：Protein phosphatase 1 regulatory subunit 14D

Human Gene Id：54866

Human Swiss Prot No：Q9NXH3

Mouse Swiss Prot No：Q7TT52

Immunogen：The antiserum was produced against synthesized peptide derived from human PPP1R14D. AA range:66-115

Specificity：PPP1R14D Polyclonal Antibody detects endogenous levels of PPP1R14D protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：PPP1R14D;GBPI;Protein phosphatase 1 regulatory subunit 14D;Gastrointestinal and brain-specific PP1-inhibitory protein 1;GBPI-1

Observed Band(KD)：24kD

Background： Protein phosphatase-1 (PP1; see MIM 176875) is a major cellular phosphatase that reverses serine/threonine protein phosphorylation. PPP1R14D is a PP1 inhibitor that itself is regulated by phosphorylation (Liu et al., 2004 [PubMed 12974676]).[supplied by OMIM, Feb 2010],

Function：function:Inhibitor of PPP1CA. Has inhibitory activity only when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.,PTM:Phosphorylated on several residues.,similarity:Belongs to the PP1 inhibitor family.,tissue specificity:Detected in colon, intestine, kidney and brain cortex.,

Subcellular Location：Cytoplasm .

Expression：Detected in colon, intestine, kidney and brain cortex.