Target：RGS21

Gene Name：RGS21

Protein Name：Regulator of G-protein signaling 21 (RGS21)

Human Gene Id：431704

Human Swiss Prot No：Q2M5E4

Immunogen：Synthesized peptide derived from human protein . at AA range: 10-90

Specificity：RGS21 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：16kD

Background： Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi (see GNAI1; MIM 139310) and Gq (see GNAQ; MIM 600998) class G-alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination.[supplied by OMIM, Nov 2008],

Function：function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.,similarity:Contains 1 RGS domain.,tissue specificity:Expressed ubiquitously.,

Subcellular Location：cytoplasm,plasma membrane,

Expression：Expressed ubiquitously.