Target：Rab 40B

Gene Name：RAB40B

Protein Name：Ras-related protein Rab-40B

Human Gene Id：10966

Human Swiss Prot No：Q12829

Mouse Swiss Prot No：Q8VHP8

Immunogen：The antiserum was produced against synthesized peptide derived from human RAB40B. AA range:229-278

Specificity：Rab 40B Polyclonal Antibody detects endogenous levels of Rab 40B protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：RAB40B;SEC4L;Ras-related protein Rab-40B;SOCS box-containing protein RAR;Protein Rar

Observed Band(KD)：34kD

Background： The protein encoded by this gene has similarity to a yeast protein which suggests a role of the gene product in regulating secretory vesicles. [provided by RefSeq, Jul 2008],

Function：domain:The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.,function:May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the small GTPase superfamily. Rab family.,similarity:Contains 1 SOCS box domain.,

Subcellular Location：Cell membrane ; Lipid-anchor ; Cytoplasmic side .

Expression： Brain,Hippocampus,