Target：Rab 2B

Gene Name：RAB2B

Protein Name：Ras-related protein Rab-2B

Human Gene Id：84932

Human Swiss Prot No：Q8WUD1

Mouse Gene Id：76338

Mouse Swiss Prot No：P59279

Immunogen：The antiserum was produced against synthesized peptide derived from human RAB2B. AA range:103-152

Specificity：Rab 2B Polyclonal Antibody detects endogenous levels of Rab 2B protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：RAB2B;Ras-related protein Rab-2B

Observed Band(KD)：24kD

Background： Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking; see MIM 179508.[supplied by OMIM, Apr 2006],

Function：function:Required for protein transport from the endoplasmic reticulum to the Golgi complex .,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Expressed in kidney, prostate, lung, liver, thymus, colon, pancreas, and skeletal muscle, and low levels in placenta. Not detected in heart, brain, spleen, testis, ovary, small intestine and leukocyte.,

Subcellular Location：Cell membrane ; Lipid-anchor ; Cytoplasmic side . Endoplasmic reticulum membrane ; Lipid-anchor . Golgi apparatus membrane ; Lipid-anchor . Cytoplasmic vesicle, secretory vesicle, acrosome . Localized in the Golgi apparatus in the round spermatids and in the acrosome in the elongating spermatid. .

Expression：Expressed in kidney, prostate, lung, liver, thymus, colon, pancreas, and skeletal muscle, and low levels in placenta. Not detected in heart, brain, spleen, testis, ovary, small intestine and leukocyte.