Target:Rab 18
Gene Name:RAB18
Protein Name:Ras-related protein Rab-18
Human Gene Id:22931
Human Swiss Prot No:Q9NP72
Mouse Gene Id:19330
Mouse Swiss Prot No:P35293
Rat Gene Id:307039
Rat Swiss Prot No:Q5EB77
Immunogen:The antiserum was produced against synthesized peptide derived from human RAB18. AA range:103-152
Specificity:Rab 18 Polyclonal Antibody detects endogenous levels of Rab 18 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:RAB18;Ras-related protein Rab-18
Observed Band(KD):28kD
Background: The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],
Function:function:Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes.,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Ubiquitous.,
Subcellular Location:Apical cell membrane . Lipid droplet .
Expression:Ubiquitous.