Target：QM

Fields：Ribosome;Coronavirus disease - COVID-19

Gene Name：RPL10

Protein Name：60S ribosomal protein L10

Human Gene Id：6134

Human Swiss Prot No：P27635

Mouse Gene Id：110954

Mouse Swiss Prot No：Q6ZWV3

Rat Gene Id：81764

Rat Swiss Prot No：Q6PDV7

Immunogen：The antiserum was produced against synthesized peptide derived from human 60S Ribosomal Protein L10. AA range:1-50

Specificity：QM Polyclonal Antibody detects endogenous levels of QM protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：RPL10;DXS648E;QM;60S ribosomal protein L10;Laminin receptor homolog;Protein QM;Tumor suppressor QM

Observed Band(KD)：25kD

Background： This gene encodes a ribosomal protein that is a component of the 60S ribosome subunit. The related protein in chicken can bind to c-Jun and can repress c-Jun-mediated transcriptional activation. Some studies have detected an association between variation in this gene and autism spectrum disorders, though others do not detect this relationship. There are multiple pseudogenes of this gene dispersed throughout the genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],

Function：developmental stage:Down-regulated during adipocyte, kidney, and heart differentiation.,disease:Defects in RPL10 may be the cause of susceptibility to X-linked autism [MIM:209850]. Autism is a pervasive developmental disorder (PDD), prototypically characterized by impairments in reciprocal social interaction and communication, restricted and stereotyped patterns of interests and activities, and the presence of developmental abnormalities by 3 years of age.,similarity:Belongs to the ribosomal protein L10e family.,

Subcellular Location：endoplasmic reticulum,cytosol,ribosome,membrane,cytosolic large ribosomal subunit,

Expression： Brain,Human lung,Mammary cancer,Mammary gland,Ovarian carcinoma,Pancreatic cancer,P