Target:RAB32
Gene Name:RAB32
Protein Name:Ras-related protein Rab-32
Human Gene Id:10981
Human Swiss Prot No:Q13637
Mouse Swiss Prot No:Q9CZE3
Immunogen:Synthesized peptide derived from human protein . at AA range: 160-240
Specificity:RAB32 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):24kD
Background: The protein encoded by this gene anchors the type II regulatory subunit of protein kinase A to the mitochondrion and aids in mitochondrial fission. The encoded protein also appears to be involved in autophagy and melanosome secretion. Variations in this gene may be linked to leprosy. [provided by RefSeq, Dec 2015],
Function:function:Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission.,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Widely expressed with high levels in heart, liver, kidney, bone marrow, testis, colon and fetal lung.,
Subcellular Location:Mitochondrion . Mitochondrion outer membrane ; Lipid-anchor . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome . Melanosome membrane . Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). The BLOC-3 complex, a heterodimer of HPS1 and HPS4 promotes its membrane localization (PubMed:23084991). .
Expression:Widely expressed with high levels in heart, liver, kidney, bone marrow, testis, colon and fetal lung.