Target：RAB1A

Fields：Autophagy - animal;Amyotrophic lateral sclerosis;Pathways of neurodegeneration - multiple diseases;Pathogenic Escherichia coli infection;Legionellosis

Gene Name：RAB1A RAB1

Protein Name：Ras-related protein Rab-1A (YPT1-related protein)

Human Gene Id：5861

Human Swiss Prot No：P62820

Mouse Swiss Prot No：P62821

Rat Swiss Prot No：Q6NYB7

Immunogen：Synthesized peptide derived from human protein . at AA range: 50-130

Specificity：RAB1A Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：22kD

Background： This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms. [provided by RefSeq, Oct 2008],

Function：function:Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity.,PTM:Phosphorylated by CDC2 kinase during mitosis.,similarity:Belongs to the small GTPase superfamily. Rab family.,subunit:May interact with YIPF5.,

Subcellular Location：Golgi apparatus . Endoplasmic reticulum . Early endosome . Cytoplasm, cytosol . Membrane . Melanosome . Alternates between membrane-associated and cytosolic forms. .

Expression： Brain,Colon,Placenta,Platelet,Tongue,