Target：RASSF8
Gene Name：RASSF8
Protein Name：Ras association domain-containing protein 8
Human Gene Id：11228
Human Swiss Prot No：Q8NHQ8
Mouse Swiss Prot No：Q8CJ96
Immunogen：Synthesized peptide derived from RASSF8 . at AA range: 60-140
Specificity：RASSF8 Polyclonal Antibody detects endogenous levels of RASSF8 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：RASSF8;C12orf2;Ras association domain-containing protein 8;Carcinoma-associated protein HOJ-1
Observed Band(KD)：48kD
Background： This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011],
Function：disease:A chromosomal aberration involving RASSF8 is found in a complex type of synpolydactyly, also referred to as 3/3-prime/4 synpolydactyly associated with metacarpal and metatarsal synostoses [MIM:608180]. Reciprocal translocation t(12;22)(p11.2;q13.3) with FBLN1.,similarity:Contains 1 Ras-associating domain.,tissue specificity:Widely expressed as a 6.2 kb transcript. A 2.2 kb alternatively spliced transcript is expressed exclusively in testis.,
Expression：Widely expressed as a 6.2 kb transcript. A 2.2 kb alternatively spliced transcript is expressed exclusively in testis.
