Target:RGF1B
Gene Name:RASGEF1B GPIG4
Protein Name:Ras-GEF domain-containing family member 1B (GPI gamma-4)
Human Gene Id:153020
Human Swiss Prot No:Q0VAM2
Mouse Swiss Prot No:Q8JZL7
Immunogen:Synthesized peptide derived from human protein . at AA range: 410-490
Specificity:RGF1B Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):52kD
Background:function:Guanine nucleotide exchange factor (GEF) for Ras family proteins (in vitro).,induction:Up-regulated in monocytes stimulated with T.cruzi GPI-anchored mucins or bacterial lipopolysaccharide.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 Ras-GEF domain.,
Function:function:Guanine nucleotide exchange factor (GEF) for Ras family proteins (in vitro).,induction:Up-regulated in monocytes stimulated with T.cruzi GPI-anchored mucins or bacterial lipopolysaccharide.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 Ras-GEF domain.,
Subcellular Location:Early endosome . Late endosome . Midbody . May shuttle between early and late endosomes (By similarity). Localizes to midbody at telophase. .
Expression: Blood,Teratocarcinoma,