Target：TB10B

Gene Name：TBC1D10B FP2461

Protein Name：TBC1 domain family member 10B (Rab27A-GAP-beta)

Human Gene Id：26000

Human Swiss Prot No：Q4KMP7

Mouse Swiss Prot No：Q8BHL3

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：TB10B Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：88kD

Background：TBC1 domain family member 10B(TBC1D10B) Homo sapiens Small G proteins of the RAB family (see MIM 179508) function in intracellular vesicle trafficking by switching from the GTP-bound state to the GDP-bound state with the assistance of guanine nucleotide exchange factors (GEFs; see MIM 609700) and GTPase-activating proteins (GAPs). TBC1D10B functions as a GAP for several proteins of the Rab family (Ishibashi et al., 2009 [PubMed 19077034]).[supplied by OMIM, Nov 2010],

Function：function:May act as a GTPase-activating protein.,similarity:Contains 1 Rab-GAP TBC domain.,

Subcellular Location：Cytoplasm . In melanocytes, located at the periphery of cells.

Expression： Brain,Epithelium,Ovary,Placenta,PNS,Teratocarcinoma,Testis,Uterus,