Target:TASK-5
Gene Name:KCNK15
Protein Name:Potassium channel subfamily K member 15
Human Gene Id:60598
Human Swiss Prot No:Q9H427
Immunogen:The antiserum was produced against synthesized peptide derived from human KCNK15. AA range:273-322
Specificity:TASK-5 Polyclonal Antibody detects endogenous levels of TASK-5 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:KCNK15;TASK5;Potassium channel subfamily K member 15;Acid-sensitive potassium channel protein TASK-5;TWIK-related acid-sensitive K(+) channel 5;Two pore potassium channel KT3.3;Two pore K(+) channel KT3.3
Observed Band(KD):42kD
Background:potassium two pore domain channel subfamily K member 15(KCNK15) Homo sapiens This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008],
Function:function:Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel.,polymorphism:Three variant polypeptides are known: TASK-5A, TASK-5B and TASK-5C. The sequence shown is that of TASK-5C.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Heterodimer .,tissue specificity:Detected in pancreas, heart, placenta, lung, liver, kidney, ovary, testis, skeletal muscle and adrenal gland, and at lower levels in prostate, spleen and thyroid gland.,
Subcellular Location:Membrane; Multi-pass membrane protein.
Expression:Detected in pancreas, heart, placenta, lung, liver, kidney, ovary, testis, skeletal muscle and adrenal gland, and at lower levels in prostate, spleen and thyroid gland.