Target:RCL
Gene Name:RCL
Protein Name:Deoxyribonucleoside 5'-monophosphate N-glycosidase
Human Gene Id:10591
Human Swiss Prot No:O43598
Mouse Swiss Prot No:Q80VJ3
Immunogen:The antiserum was produced against synthesized peptide derived from human RCL. AA range:1-50
Specificity:RCL Polyclonal Antibody detects endogenous levels of RCL protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000;IHC 1:50-300
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:RCL;C6orf108;Deoxyribonucleoside 5'-monophosphate N-glycosidase;c-Myc-responsive protein Rcl
Observed Band(KD):22kD
Background: This gene was identified on the basis of its stimulation by c-Myc protein. The latter is a transcription factor that participates in the regulation of cell proliferation, differentiation, and apoptosis. The exact function of this gene is not known but studies in rat suggest a role in cellular proliferation and c-Myc-mediated transformation. Two alternative transcripts encoding different proteins have been described. [provided by RefSeq, Jul 2008],
Function:caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:May play a role during cellular proliferation and c-Myc-mediated transformation.,tissue specificity:Expression is elevated in lymphoid cells that overexpress c-Myc.,
Subcellular Location:Cytoplasm . Nucleus .
Expression:Expressed at low levels in brain, colon, lung, peripheral blood leukocytes, placenta, small intestine, and thymus. Expressed at high levels in heart, kidney, liver, skeletal muscle and spleen. Overexpressed in a significant proportion of breast cancers.