Target：RBMS1

Gene Name：RBMS1 C2orf12 MSSP MSSP1 SCR2

Protein Name：RNA-binding motif, single-stranded-interacting protein 1 (Single-stranded DNA-binding protein MSSP-1) (Suppressor of CDC2 with RNA-binding motif 2)

Human Gene Id：5937

Human Swiss Prot No：P29558

Mouse Swiss Prot No：Q91W59

Rat Swiss Prot No：Q5PQP1

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：RBMS1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：44kD

Background： This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12. [provided by RefSeq, Feb 2009],

Function：developmental stage:Expressed at highest levels during the G1 to S transition of the cell cycle.,function:Single-stranded DNA binding protein that interacts with the region upstream of the C-myc gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication.,sequence caution:Translation N-terminally extended.,similarity:Contains 2 RRM (RNA recognition motif) domains.,tissue specificity:Highest amounts are found in placenta, lung and heart.,

Subcellular Location：Nucleus.

Expression：Highest amounts are found in placenta, lung and heart.