Target：TCP-1 ζ
Gene Name：CCT6A
Protein Name：T-complex protein 1 subunit zeta
Human Gene Id：908
Human Swiss Prot No：P40227
Mouse Gene Id：12466
Mouse Swiss Prot No：P80317
Immunogen：The antiserum was produced against synthesized peptide derived from human CCT6A. AA range:171-220
Specificity：TCP-1 ζ Polyclonal Antibody detects endogenous levels of TCP-1 ζ protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：CCT6A;CCT6;CCTZ;T-complex protein 1 subunit zeta;TCP-1-zeta;Acute morphine dependence-related protein 2;CCT-zeta-1;HTR3;Tcp20
Observed Band(KD)：60kD
Background： The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, several pseudogenes of this gene have been located. [provided by RefSeq, Jun 2010],
Function：caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.,similarity:Belongs to the TCP-1 chaperonin family.,subunit:Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter. Interacts with PACRG.,
Subcellular Location：Cytoplasm .
Expression： B-cell,Brain,Cajal-Retzius cell,Platelet,
