Target：TCF25

Gene Name：TCF25 KIAA1049 NULP1 FKSG26

Protein Name：Transcription factor 25 (TCF-25) (Nuclear localized protein 1)

Human Gene Id：22980

Human Swiss Prot No：Q9BQ70

Mouse Swiss Prot No：Q8R3L2

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：TCF25 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：74kD

Background： TCF25 is a member of the basic helix-loop-helix (bHLH) family of transcription factors that are important in embryonic development (Steen and Lindholm, 2008 [PubMed 18068114]).[supplied by OMIM, Sep 2008],

Function：domain:The C-terminal region mediates transcriptional repression.,function:May play a role in cell death control. Acts as a transcriptional repressor. Has been shown to repress transcription of SRF in vitro and so may play a role in heart development.,similarity:Belongs to the TCF25 family.,subcellular location:Some staining in the cytosol.,subunit:Interacts with XIAP.,tissue specificity:In the embryo, widely expressed with highest levels in brain. In the adult, highest expression is found in the heart.,

Subcellular Location：Nucleus . Some staining in the cytosol.

Expression：In the embryo, widely expressed with highest levels in brain. In the adult, highest expression is found in the heart.