Target：THIOM

Fields：NOD-like receptor signaling pathway;Parkinson disease;Salmonella infection;Fluid shear stress and atherosclerosis

Gene Name：TXN2 TRX2

Protein Name：Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2)

Human Gene Id：25828

Human Swiss Prot No：Q99757

Mouse Swiss Prot No：P97493

Rat Swiss Prot No：P97615

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：THIOM Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：18kD

Background： This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. [provided by RefSeq, Jul 2008],

Function：function:Has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Could be involved in the resistance to anti-tumor agents. Possesses a dithiol-reducing activity.,similarity:Belongs to the thioredoxin family.,similarity:Contains 1 thioredoxin domain.,subunit:Monomer.,tissue specificity:Widely expressed in adult (at protein level) and fetal tissues.,

Subcellular Location：Mitochondrion .

Expression：Widely expressed in adult (at protein level) and fetal tissues.