Target:TFIIE-β
Fields:Basal transcription factors;Viral carcinogenesis
Gene Name:GTF2E2
Protein Name:Transcription initiation factor IIE subunit beta
Human Gene Id:2961
Human Swiss Prot No:P29084
Mouse Gene Id:68153
Mouse Swiss Prot No:Q9D902
Immunogen:The antiserum was produced against synthesized peptide derived from human TF2E2. AA range:151-200
Specificity:TFIIE-β Polyclonal Antibody detects endogenous levels of TFIIE-β protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:GTF2E2;TF2E2;Transcription initiation factor IIE subunit beta;TFIIE-beta;General transcription factor IIE subunit 2
Observed Band(KD):33kD
Background:function:Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.,similarity:Belongs to the TFIIE beta subunit family.,similarity:Contains 1 TFIIE beta DNA-binding domain.,subunit:Tetramer of two alpha and two beta chains. Interacts with FACT subunit SUPT16H.,
Function:function:Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.,similarity:Belongs to the TFIIE beta subunit family.,similarity:Contains 1 TFIIE beta DNA-binding domain.,subunit:Tetramer of two alpha and two beta chains. Interacts with FACT subunit SUPT16H.,
Subcellular Location:Nucleus .
Expression: Skin,