Target：TFF2

Gene Name：TFF2 SML1

Protein Name：Trefoil factor 2 (Spasmolysin) (Spasmolytic polypeptide) (SP)

Human Gene Id：7032

Human Swiss Prot No：Q03403

Mouse Swiss Prot No：Q03404

Rat Swiss Prot No：Q09030

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：TFF2 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：14kD

Background： Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008],

Function：function:Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains.,similarity:Contains 2 P-type (trefoil) domains.,tissue specificity:Stomach.,

Subcellular Location：Secreted.

Expression：Stomach.