Target：TMPS5

Gene Name：TMPRSS5

Protein Name：Transmembrane protease serine 5 (EC 3.4.21.-) (Spinesin)

Human Gene Id：80975

Human Swiss Prot No：Q9H3S3

Mouse Swiss Prot No：Q9ER04

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：TMPS5 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：50kD

Background： This gene encodes a protein that belongs to the serine protease family. Serine proteases are known to be involved in many physiological and pathological processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],

Function：disease:Defects in TMPRSS5 may be a cause of deafness.,function:May play a role in hearing.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 1 SRCR domain.,tissue specificity:Brain-specific. Predominantly expressed in neurons, in their axons, and at the synapses of motoneurons in the spinal cord.,

Subcellular Location：Cell membrane ; Single-pass type II membrane protein .

Expression：Brain-specific. Predominantly expressed in neurons, in their axons, and at the synapses of motoneurons in the spinal cord.