Target：TMM74

Gene Name：TMEM74

Protein Name：Transmembrane protein 74

Human Gene Id：157753

Human Swiss Prot No：Q96NL1

Mouse Swiss Prot No：Q8BQU7

Immunogen：Synthesized peptide derived from human protein . at AA range: 181-230

Specificity：TMM74 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：33kD

Background：TMEM74 (Transmembrane Protein 74) is a Protein Coding gene. An important paralog of this gene is TMEM74B. Plays an essential role in autophagy. TMEM74-induced autophagy may involve PI3K signal transduction.

Function：autophagy,

Subcellular Location：Lysosome membrane ; Multi-pass membrane protein . Cytoplasmic vesicle, autophagosome membrane ; Multi-pass membrane protein .

Expression：Expressed in heart, lung, and placenta.