Target:TIPRL
Gene Name:TIPRL
Protein Name:TIP41-like protein (Putative MAPK-activating protein PM10) (Type 2A-interacting protein) (TIP)
Human Gene Id:261726
Human Swiss Prot No:O75663
Mouse Swiss Prot No:Q8BH58
Rat Swiss Prot No:A2VCX1
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:TIPRL Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):29kD
Background: TIPRL is an inhibitory regulator of protein phosphatase-2A (PP2A) (see PPP2CA; MIM 176915), PP4 (see PPP4C; MIM 602035), and PP6 (see PPP6C; MIM 612725) (McConnell et al., 2007 [PubMed 17384681]).[supplied by OMIM, Nov 2010],
Function:PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the TIP41 family.,
Subcellular Location:Cytoplasm .
Expression: Fetal kidney,Lung fibroblast,Muscle,