Target：TXND2

Gene Name：TXNDC2 SPTRX SPTRX1

Protein Name：Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1)

Human Gene Id：84203

Human Swiss Prot No：Q86VQ3

Mouse Swiss Prot No：Q6P902

Rat Swiss Prot No：Q5XHX6

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：TXND2 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：60kD

Background：function:Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase.,similarity:Contains 1 thioredoxin domain.,subcellular location:In ejaculated spermatozoa, it localizes in the caudal region of the head to the end of the principal piece.,tissue specificity:Testis-specific. Only expressed during spermiogenesis, prominently in round and elongating spermatids.,

Function：function:Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase.,similarity:Contains 1 thioredoxin domain.,subcellular location:In ejaculated spermatozoa, it localizes in the caudal region of the head to the end of the principal piece.,tissue specificity:Testis-specific. Only expressed during spermiogenesis, prominently in round and elongating spermatids.,

Subcellular Location：Cytoplasm . In ejaculated spermatozoa, it localizes in the caudal region of the head to the end of the principal piece.

Expression：Testis-specific. Only expressed during spermiogenesis, prominently in round and elongating spermatids.