Target:TRAK1
Gene Name:TRAK1 KIAA1042 OIP106
Protein Name:Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein)
Human Gene Id:22906
Human Swiss Prot No:Q9UPV9
Mouse Swiss Prot No:Q6PD31
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:TRAK1 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):104kD
Background:PTM:O-glycosylated.,similarity:Contains 1 HAP1 N-terminal domain.,subunit:Interacts with O-GlcNAc transferase. Interacts with RHOT1/Miro-1 and RHOT2/Miro-2.,tissue specificity:High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Expressed in all cell lines examined.,
Function:PTM:O-glycosylated.,similarity:Contains 1 HAP1 N-terminal domain.,subunit:Interacts with O-GlcNAc transferase. Interacts with RHOT1/Miro-1 and RHOT2/Miro-2.,tissue specificity:High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Expressed in all cell lines examined.,
Subcellular Location:Cytoplasm . Nucleus . Mitochondrion . Early endosome . Endosome . Mitochondrion membrane . Cytoplasm, cell cortex . Predominantly associated with early endosome. The localization to early endosomes depends on its interaction with HGS/HRS (PubMed:18675823). Colocalizes with MGARP at the mitochondria (PubMed:19528298). .
Expression:High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Expressed in all cell lines examined.