Target:Tra-2α
Fields:Spliceosome;Alcoholic liver disease
Gene Name:TRA2A
Protein Name:Transformer-2 protein homolog alpha
Human Gene Id:29896
Human Swiss Prot No:Q13595
Mouse Swiss Prot No:Q6PFR5
Immunogen:The antiserum was produced against synthesized peptide derived from human TRA-2 alpha. AA range:221-270
Specificity:Tra-2α Polyclonal Antibody detects endogenous levels of Tra-2α protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:TRA2A;Transformer-2 protein homolog alpha;TRA-2 alpha;TRA2-alpha;Transformer-2 protein homolog A
Observed Band(KD):33kD
Background: This gene is a member of the transformer 2 homolog family and encodes a protein with several RRM (RNA recognition motif) domains. This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre-mRNA splicing. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013],
Function:function:Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing.,PTM:Phosphorylated in the RS domains.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Binds to A3 enhancer proteins SRp75, SRp55, SRp40 and SRp30.,
Subcellular Location:Nucleus .
Expression: Cervix carcinoma,Epithelium,Hepatocyte,Lung,Testis,Uterus,