Target：VGF

Fields：Neuroactive ligand-receptor interaction

Gene Name：VGF

Protein Name：Neurosecretory protein VGF

Human Gene Id：7425

Human Swiss Prot No：O15240

Rat Gene Id：29461

Rat Swiss Prot No：P20156

Immunogen：The antiserum was produced against synthesized peptide derived from the Internal region of human VGF. AA range:451-500

Specificity：VGF Polyclonal Antibody detects endogenous levels of VGF protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：VGF;Neurosecretory protein VGF

Observed Band(KD)：67kD

Background： This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. [provided by RefSeq, Jul 2008],

Function：function:May be involved in the regulation of cell-cell interactions or in synatogenesis during the maturation of the nervous system.,subcellular location:Stored in secretory vesicles and then secreted.,tissue specificity:Expressed in brain.,

Subcellular Location：[Neurosecretory protein VGF]: Secreted . Cytoplasmic vesicle, secretory vesicle . Stored in secretory vesicles and then secreted, NERP peptides colocalize with vasopressin in the storage granules of hypothalamus.

Expression：Central and peripheral nervous systems, synthesized exclusively in neuronal and neuroendocrine cells.