Target:USP43
Gene Name:USP43
Protein Name:Ubiquitin carboxyl-terminal hydrolase 43
Human Gene Id:124739
Human Swiss Prot No:Q70EL4
Mouse Gene Id:216835
Mouse Swiss Prot No:Q8BUM9
Immunogen:Synthesized peptide derived from the N-terminal region of human USP43.
Specificity:USP43 Polyclonal Antibody detects endogenous levels of USP43 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:USP43;Ubiquitin carboxyl-terminal hydrolase 43;Deubiquitinating enzyme 43;Ubiquitin thioesterase 43;Ubiquitin-specific-processing protease 43
Observed Band(KD):125kD
Background:catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:May recognize and hydrolyze the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquinated proteins.,similarity:Belongs to the peptidase C19 family.,tissue specificity:Expressed in brain, aorta and lung at low levels.,
Function:catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:May recognize and hydrolyze the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquinated proteins.,similarity:Belongs to the peptidase C19 family.,tissue specificity:Expressed in brain, aorta and lung at low levels.,
Subcellular Location:nucleoplasm,
Expression:Expressed in brain, aorta and lung at low levels.