Target：TS1R1

Fields：Taste transduction

Gene Name：TAS1R1 GPR70 T1R1 TR1 GM148

Protein Name：Taste receptor type 1 member 1 (G-protein coupled receptor 70)

Human Gene Id：80835

Human Swiss Prot No：Q7RTX1

Mouse Swiss Prot No：Q99PG6

Rat Swiss Prot No：Q9Z0R8

Immunogen：Synthesized peptide derived from human protein . at AA range: 280-360

Specificity：TS1R1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：92kD

Background： The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010],

Function：function:Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.,online information:The taste experience -Issue 55 of February 2005,similarity:Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily.,subunit:Forms heterodimers with TAS1R3.,

Subcellular Location：Cell membrane; Multi-pass membrane protein.