Target：USP40

Gene Name：USP40

Protein Name：Ubiquitin carboxyl-terminal hydrolase 40

Human Gene Id：55230

Human Swiss Prot No：Q9NVE5

Mouse Swiss Prot No：Q8BWR4

Immunogen：The antiserum was produced against synthesized peptide derived from human USP40. AA range:1011-1060

Specificity：USP40 Polyclonal Antibody detects endogenous levels of USP40 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：USP40;Ubiquitin carboxyl-terminal hydrolase 40;Deubiquitinating enzyme 40;Ubiquitin thioesterase 40;Ubiquitin-specific-processing protease 40

Observed Band(KD)：140kD

Background： Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP40 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008],

Function：catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:May be catalytically inactive.,similarity:Belongs to the peptidase C19 family.,tissue specificity:Broadly expressed.,

Subcellular Location：nucleus,cytoplasm,

Expression：Broadly expressed.