Target：USP36

Gene Name：USP36

Protein Name：Ubiquitin carboxyl-terminal hydrolase 36

Human Gene Id：57602

Human Swiss Prot No：Q9P275

Mouse Swiss Prot No：B1AQJ2

Immunogen：The antiserum was produced against synthesized peptide derived from human USP36. AA range:501-550

Specificity：USP36 Polyclonal Antibody detects endogenous levels of USP36 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：USP36;KIAA1453;Ubiquitin carboxyl-terminal hydrolase 36;Deubiquitinating enzyme 36;Ubiquitin thioesterase 36;Ubiquitin-specific-processing protease 36

Observed Band(KD)：125kD

Background： This gene encodes a member of the peptidase C19 or ubiquitin-specific protease family of cysteine proteases. Members of this family remove ubiquitin molecules from polyubiquitinated proteins. The encoded protein may deubiquitinate and stabilize the transcription factor c-Myc, also known as MYC, an important oncoprotein known to be upregulated in most human cancers. The encoded protease may also regulate the activation of autophagy. This gene exhibits elevated expression in some breast and lung cancers. [provided by RefSeq, Mar 2016],

Function：catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,similarity:Belongs to the peptidase C19 family.,tissue specificity:Broadly expressed.,

Subcellular Location：Nucleus, nucleolus . Cytoplasm .

Expression：Broadly expressed.