Target：USP24

Gene Name：USP24

Protein Name：Ubiquitin carboxyl-terminal hydrolase 24

Human Gene Id：23358

Human Swiss Prot No：Q9UPU5

Mouse Gene Id：329908

Mouse Swiss Prot No：B1AY13

Immunogen：The antiserum was produced against synthesized peptide derived from human USP24. AA range:21-70

Specificity：USP24 Polyclonal Antibody detects endogenous levels of USP24 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：USP24;KIAA1057;Ubiquitin carboxyl-terminal hydrolase 24;Deubiquitinating enzyme 24;Ubiquitin thioesterase 24;Ubiquitin-specific-processing protease 24

Molecular Weight(Da)：211kD

Background： Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008],

Function：catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 UBA domain.,

Subcellular Location：cytoplasm,

Expression： Brain,Epithelium,Placenta,Platelet,T-cell,