Target：USP19
Gene Name：USP19
Protein Name：Ubiquitin carboxyl-terminal hydrolase 19
Human Gene Id：10869
Human Swiss Prot No：O94966
Mouse Gene Id：71472
Mouse Swiss Prot No：Q3UJD6
Rat Gene Id：361190
Rat Swiss Prot No：Q6J1Y9
Immunogen：The antiserum was produced against synthesized peptide derived from human USP19. AA range:391-440
Specificity：USP19 Polyclonal Antibody detects endogenous levels of USP19 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：USP19;KIAA0891;ZMYND9;Ubiquitin carboxyl-terminal hydrolase 19;Deubiquitinating enzyme 19;Ubiquitin thioesterase 19;Ubiquitin-specific-processing protease 19;Zinc finger MYND domain-containing protein 9
Observed Band(KD)：130kD
Background：catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Translation N-terminally shortened.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 MYND-type zinc finger.,similarity:Contains 2 CS domains.,
Function：catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Translation N-terminally shortened.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 MYND-type zinc finger.,similarity:Contains 2 CS domains.,
Subcellular Location：Endoplasmic reticulum membrane ; Single-pass membrane protein .
Expression： Brain,Epithelium,Skin,Testis,
