Target：WDHD1

Gene Name：WDHD1

Protein Name：WD repeat and HMG-box DNA-binding protein 1

Human Gene Id：11169

Human Swiss Prot No：O75717

Mouse Swiss Prot No：P59328

Immunogen：The antiserum was produced against synthesized peptide derived from human WDHD1. AA range:721-770

Specificity：WDHD1 Polyclonal Antibody detects endogenous levels of WDHD1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：WDHD1;AND1;WD repeat and HMG-box DNA-binding protein 1;Acidic nucleoplasmic DNA-binding protein 1;And-1

Observed Band(KD)：126kD

Background： The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Function：caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Binds DNA with high affinity. May also be involved in protein-protein interactions.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 HMG box DNA-binding domain.,similarity:Contains 7 WD repeats.,

Subcellular Location：Nucleus, nucleoplasm .

Expression： Embryonal rhabdomyosarcoma,Epithelium,Fetal brain,Liver,Ski