Target：VSIG4

Fields：Complement and coagulation cascades

Gene Name：VSIG4 CRIg Z39IG UNQ317/PRO362

Protein Name：V-set and immunoglobulin domain-containing protein 4 (Protein Z39Ig)

Human Gene Id：11326

Human Swiss Prot No：Q9Y279

Immunogen：Synthesized peptide derived from human protein . at AA range: 70-150

Specificity：VSIG4 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：43kD

Background： This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010],

Function：function:Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases.,similarity:Contains 2 Ig-like (immunoglobulin-like) domains.,tissue specificity:Abundantly expressed in several fetal tissues. In adult tissues, highest expression in lung and placenta. Expressed in resting macrophages.,

Subcellular Location：Membrane ; Single-pass type I membrane protein .

Expression：Abundantly expressed in several fetal tissues. In adult tissues, highest expression in lung and placenta. Expressed in resting macrophages.