Target:VPS54
Gene Name:VPS54
Protein Name:Vacuolar protein sorting-associated protein 54
Human Gene Id:51542
Human Swiss Prot No:Q9P1Q0
Mouse Swiss Prot No:Q5SPW0
Immunogen:Synthesized peptide derived from the Internal region of human VPS54.
Specificity:VPS54 Polyclonal Antibody detects endogenous levels of VPS54 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:VPS54;HCC8;Vacuolar protein sorting-associated protein 54;Hepatocellular carcinoma protein 8;Tumor antigen HOM-HCC-8;Tumor antigen SLP-8p
Molecular Weight(Da):111kD
Background: This gene encodes for a protein that in yeast forms part of a trimeric vacuolar-protein-sorting complex that is required for retrograde transport of proteins from prevacuoles to the late Golgi compartment. As in yeast, mammalian Vps54 proteins contain a coiled-coil region and dileucine motifs. Alternative splicing results in multiple transcript variants encoding different isoforms [provided by RefSeq, Jul 2008],
Function:function:May be involved in retrograde transport from early and late endosomes to late Golgi.,similarity:Belongs to the VPS54 family.,subunit:Component of the Golgi-associated retrograde protein (GARP) complex, also called VFT (VPS fifty-three) complex, composed of VPS52, VPS53 and VPS54.,
Subcellular Location:Golgi apparatus, trans-Golgi network . Membrane . Associates with membranes in an EIPR1-independent manner. .
Expression: Hepatoma,Placenta,Skin,Testis,